Health Diabetes GABA treatment Laurie Marzell, ND

Reversing Diabetes Type I

Dr. Jonathan Wright wrote in a recent newsletter an article about using nutrients to actually reverse diabetes type I.  I reviewed the research which is fascinating and holds promise for human treatment of this disease.  Interestingly, GABA, a brain neurotransmitter, has been found to be produced by the B cells of the pancreas.  These are the cells which produce insulin, and are attacked and killed by the person’s own immune system in an autoimmune reaction.  This just about wipes out the body’s insulin; needed for transporting glucose into the cells to be used for energy.  This drives up the blood sugar, causing all kinds of havoc in the body.

One study showed if mice were injected with GABA before being exposed to chemicals which kill their B cells; there is less destruction of the cells (85% without GABA vs. 15% with GABA).  The “GABA mice” did not develop diabetes and had nearly normal insulin levels and B cell mass.  In a further study, another group of mice, who had developed severe diabetes type I, were given GABA injections, and found to regain some of their B cell mass, improved their insulin levels and lowered their blood sugar levels.  In other words, the injected GABA, helped to repair and reverse the damage the mice had experienced to their pancreatic cells.

Another study is equally exciting, involving one of my favorite nutrients, niacinamide.  In this study, niacinamide was added to stem cells of mice.  It changed them into insulin secreting cells, which were transplanted into diabetic mice, used to “reverse” their diabetes.  Stem cells normally are present in various organs, so orally supplementing with this nutrient may help stimulate the body’s own stem cells.

Another interesting point made, was in regards to the connection between autoimmune diseases (rheumatoid arthritis, celiac disease, pernicious anemia, diabetes type I) and cow’s milk and gluten sensitivity.  One of the reports indicate that the anti-gliadin antibodies produced by gluten sensitive people, directly inhibit and enzyme pathway that produces GABA in the pancreas.  A true Aha moment.

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